Asplenic patient with encapsulated bacteremia

A 52-year-old man with a history of traumatic splenectomy presents to the emergency department with fever, chills, and hypotension. Blood cultures grow a gram-positive, alpha-hemolytic, optochin-sensitive, catalase-negative organism. Despite aggressive fluid resuscitation and empiric broad-spectrum antibiotics, the patient remains septic. Which feature of this organism is most directly responsible for its resistance to opsonization and phagocytic clearance in this asplenic patient?

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Asplenic patient with encapsulated bacteremia | QWorld.Ai