A 30-year-old man of Turkish descent presents with a 2-year history of recurrent painful oral ulcers and more recently painful genital ulcers. He also reports episodic red nodules on his lower legs and has had two episodes of anterior uveitis in the past year. On examination, there are multiple aphthous ulcers on the buccal mucosa and erythematous tender nodules over the tibial surfaces. A pathergy test with a 20-gauge needle produces a pustular papule at 48 hours. Which of the following is the most appropriate initial therapy for this patient’s mucocutaneous lesions?